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ZOLDONAT 4mg Injection

$130.00

ZOLDONAT 4mg Injection

$130.00

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Description

Product Description

Zoldonat

ZOLDONA contain zoledronic acid which belongs to a group of medicine called bisphosphonates. It is used to prevent bone complications such as fractures, and bone metastases in adult patients and helps in reducing the amount of calcium in the blood in a condition called tumor-induced hypercalcaemia (TIH) in adult patients.
Tumour can accelerate normal bone change in such a way that the release of calcium from bone is increased.

ZOLDONA works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bone and minimize the risk of fracture.
This medicine is strictly not recommended for use in children and adolescents under 18 years of age.

Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF ZOLDONA

  • Prevent bone complications (e.g., fractures, in adult patients with bone metastases (spread of cancer from primary site to the bone))
  • Reduce the amount of calcium in tumour-induced hypercalcaemia (TIH) in adult patients

HOW ZOLDONA WORKS

ZOLDONA works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bone and minimize the risk of fracture.

DIRECTIONS FOR USE

ZOLDONA will be administered by a doctor or nurse. It will be given as a drip (infusion) into a vein. Your doctor will decide the dose and frequency depending on your condition.

SIDE EFFECTS OF ZOLDONA

SERIOUS

  • Severe kidney impairment
  • Low level of calcium in the blood

COMMON

  • Low level of phosphate in the blood
  • Headache
  • Flu-like syndrome such as fever, fatigue, weakness, drowsiness, chills, and bone, joint and/or muscle ache
  • Gastrointestinal reaction such as nausea, vomiting, loss of appetite
  • Conjunctivitis
  • Low level of red blood cells (anaemia)

RARE

  • Slow heartbeat
  • Confusion
  • Unusual fracture of the thigh bone
  • Discomfort in your thigh, hip
  • Interstitial lung disease (inflammation of the tissue around the air sacks of the lungs)

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Fever:

Drink plenty of fluids and water. Avoid taking cold bath or showers.

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

INTERACTIONS

Talk to your doctor if you are taking,

  • Aminoglycosides (used to treat severe infections)
  • Thalidomide (used to treat a certain type of blood cancer involving the bone)
  • Anti-angiogenic medicines (used to treat cancer)

SYNOPSIS

Drug : Zoledronic acid
Pharmacological Category : Bisphosphonate Derivative
Therapeutic Indication : Bone complications
Dosage Forms : Injection

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ZOLDONA

Can I take ZOLDONA during pregnancy?

No, it is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your Doctor.

Can I take ZOLDONA during breastfeeding?

No, it is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your Doctor.

Can ZOLDONA cause headache?

Yes, this medicine may cause headache in some individuals. Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

PRODUCT INTRODUCTION

Zoldonat 4 mg Injection is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids.
Using this medicine can reduce your risk of breaking bones. It is also used to treat high levels of calcium in people who have cancer.Zoldonat 4 mg Injection is given by a doctor or nurse. How much you are given, and how often, will be decided by your doctor.
ZOLDONAT 4mg Injection
It may just be a single injection or you may need regular injections depending upon your underlying condition.
Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated.

It may take several days to get the full benefit of this drug. Zoldonat 4mg Injection is only part of a treatment program that may also include changes to your diet and taking calcium and vitamin supplements. click here : Zoldonat 

most common side effects

The most common side effects include nausea, fatigue, anemia, bone pain, constipation, fever, vomiting, and breathlessness.

Zoldonat 4mg Injection can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills) or if you already have kidney disease.

It can also cause low levels of calcium in the blood and pain in the mouth or jaw.

These are serious side effects and need urgent medical attention. Tell your doctor straight away if you notice any of these.You should not be given this medicine if you are pregnant or breastfeeding.
Before taking it, tell your doctor if you have kidney problems or low calcium levels.
Also, let your doctor know what other medicines you are taking.

Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis.
You may need frequent medical tests to check your kidney function and calcium levels.

Avoid smoking as it can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.

USES OF ZOLDONAT INJECTION

  • Osteoporosis
  • Hypercalcemia

BENEFITS OF ZOLDONAT INJECTION

In Osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause.

This condition can be treated with bone-strengthening medicines. Zoldonat 4mg Injection is a type of medicine called a bisphosphonate. It slows down the rate at which bone is broken down in your body.

This maintains bone density and reduces your risk of breaking a bone. The injection is usually given once every year to treat osteoporosis and every two years to prevent it.

You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D, and reducing your consumption of alcohol and tobacco.
Supplements of calcium and Vitamin D3 are also effective.

In Hypercalcemia

Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones.
When you have more calcium in your blood than normal it is called hypercalcaemia.It is a serious condition and affects a large number of people with cancer. Zoldonat 4mg Injection is a type of medicine called a bisphosphonate.

It reduces the amount of calcium in your blood by slowing down the rate at which bone is broken down in your body.

This medicine is normally only given once by injection to treat hypercalcaemia, but you may need additional doses. Make sure you attend all appointments with your doctor.

Being immobile makes hypercalcaemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.

SIDE EFFECTS OF ZOLDONAT INJECTION

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoldonat

  • Headache
  • Back pain
  • Musculoskeletal (bone, muscle or joint) pain
  • Heartburn
  • Diarrhea
  • Nausea
  • Breathlessness
  • Fatigue
  • Constipation
  • Bone pain
  • Vomiting
  • Fever
  • Anemia (low number of red blood cells)

HOW TO USE ZOLDONAT INJECTION

Your doctor or nurse will give you this medicine. Kindly do not self administer.

HOW ZOLDONAT INJECTION WORKS

Zoldonat 4mg Injection is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

SAFETY ADVICE

warnings

Alcohol

Caution is advised when consuming alcohol with Zoldonat 4mg Injection. Please consult your doctor.
warnings

Pregnancy

Zoldonat 4mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
warnings

Breast feeding

Zoldonat 4mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
warnings

Driving

Zoldonat 4mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
warnings

Kidney

There is limited information available on the use of Zoldonat 4mg Injection in patients with kidney disease. Please consult your doctor.
warnings

Liver

There is limited information available on the use of Zoldonat 4mg Injection in patients with liver disease. Please consult your doctor.

WHAT IF YOU FORGET TO TAKE ZOLDONAT INJECTION?

If you miss a dose of Zoldonat 4mg Injection. Please consult your doctor.
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