TOPAMAC 25mg Tablet



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Topamac 25mg Tablet is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).

Topamac 25mg Tablet may be taken with or without food, preferably at the same time, each day. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better.

Stopping the medication suddenly without talking to your doctor may cause an increased frequency of seizures. Your doctor may advise regular monitoring of serum bicarbonate levels while you are taking this medicine.

Some of the common side effects of this medicine include nausea, taste change, fatigue, diarrhea, weight loss, loss of appetite, and memory impairment. It may also cause vision problems like myopia or glaucoma, so it is important to get your eyesight checked before you start the treatment and regularly thereafter.

You may experience dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Please consult your doctor if these side effects bother you or do not go away.

Topiramate is an anti seizure drug, also called as an anti convulsant. It is prescribed mainly as a standalone drug or in combination with other medications to treat seizures in adults and children who are above 2 years of age.

Topiramate is also prescribed for preventing migraine headaches in adults. This drug may also be used for conditions not described here.

Topiramate is sold under various trade names, some of which are Topamax and Topamac (made by Johnson & Johnson).


Topiramate (Topamax, Topamac) is a FDA pregnancy category D drug. Pregnant women must not start or stop taking this medication without their doctor’s advice. This medication may cause cleft lip or cleft palate in the baby if taken during pregnancy.

Topiramate may harm an unborn baby, but seizure during pregnancy can also be detrimental for both mother and baby. Let your doctor know immediately if you become pregnant while taking Topiramate. This medication can get into breast milk and may harm a nursing baby and hence Topiramate is not recommended for nursing mothers.

Topiramate has the potential of reducing the effectiveness of birth control pills. Hence, while taking this medication, an alternative form of contraception is recommended like condoms or diaphragm with spermicide.

Topiramate usage may lead to suicidal thoughts. This side effect may require you to undergo regular follow up checks by your doctor.

You must notify your doctor about any new or deteriorating symptoms like mood or behavior changes, depression, anxiety, suicidal or self hurting thoughts, increased agitation, hostility, restlessness, hyperactivity (mentally or physically).

While taking Topiramate, if you experience a sudden change in vision or pain around or behind your eyes, seek emergency medical attention. The change in vision and pain may be an early sign of a severe and permanent side effect on your vision.

Avoid stopping Topiramate medication suddenly without the advice of your doctor, even if you feel alright. Your condition may become worse with increased seizures if you stop this medication suddenly.


Keep in mind all precautions and points listed above before taking Topiramate anti convulsant medicatoin (Topamax, Topamac) and discuss them with your doctor for more clarifications.

Before taking Topiramate anti convulsant medication, let your doctor know for safe use of this medication if you have kidney or liver disease, glaucoma, history of metabolic acidosis, osteoporosis or low bone density, asthma emphysema, or other breathing disorder, past episodes of depression or suicidal thoughts, or if you are allergic to other seizure medicines.


Take Topiramate anti convulsant medication (Topamax, Topamac) strictly according to your doctor’s direction or according to the instructions on the medication label. Do not alter the dosage unless your doctor advises you to do so.

Your doctor may occasionally change the dosage over several weeks or months to ensure proper treatment. Follow your doctor’s directions properly.

Take Topiramate along with food or you may take it without food as well. Swallow a Topiramate tablet whole, chewing or breaking it in your mouth will give you an unpleasant bitter taste.

Make sure to have plenty of liquids while taking Topiramate as chances of dehydration are high while with this medication. This will also lower any chance of kidney stones or electrolyte imbalance. Inform your doctor if you have vomiting or diarrhea as this can lead to dehydration.


In Epilepsy/Seizures

Topamac 25mg Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures.
By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

In Prevention of Migraine

It is not fully established how Topamac 25mg Tablet helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines.
By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

In Lennox–Gastaut syndrome

Lennox-Gastaut syndrome (LGS) is a rare but severe form of epilepsy that usually starts in early childhood. Affected children may experience several different types of seizures. Topamac 25mg Tablet helps prevent and control these seizures by decreasing the nerve impulses which cause the seizures.


If you miss a dose and if it is not too late (more than 6 hours) since the schedule dose time, take the missed dose right away. However, you have to skip the missed dose if the time for the next dose is near. Taking two doses near to each can be dangerous.


In case of an overdose of Topiramate, get emergency medical attention or call the Doctor immediately. Overdose may lead to drowsiness, giddiness, agitation or depression, stomach or chest pain blurred vision, breathing shortness, fainting, or seizures.


Topiramate may cause blurred vision and impact your thinking capability and reflexes which can make activities like driving difficult and intimidating. Be extra careful while indulging in such activities or keep them to minimum and do it when absolutely necessary while taking this medication.

Ketogenic or “ketosis” diets which are prescribed mainly for epileptic seizures in children that are high in fats and low in carbohydrates can increase the risk of kidney stones when taken with Topiramate. Talk to your doctor about this.



• Dizziness
• Drowsiness
• Headache
• Blurred Or Double Vision With Pain Around Or Behind The Eyes
• Loss Of Coordination
• Slowed Thinking
• Shaking (Tremor)
• Nausea
• Vomiting, Or Upset Stomach


Topiramate dosage may depend on a range of factors like age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage will be fixed by your doctor after examining you properly. Remember to obey your doctor strictly for best results.


Certain medications like allergy drugs, sedatives, narcotic pain killers, sleeping pills, muscle relaxers, or anti depressants which cause sleepiness can interact with Topiramate by increasing the sleepiness caused by it. Let your doctor know if you use any of these medications.

Also let your doctor know if you use any of the following interacting drugs: lithium, hydrochlorothiazide, diabetic medications like metformin, bronchodilators such as ipratropium, atropine, belladonna, benztropine, bladder or urinary medications such as darifenacin, solifenacin or others, glaucoma medications such as acetazolamide, or other seizure medication like carbamazepine, Topiramate, phenytoin, valproic acid or others.

This list of drugs mentioned here in this guide is not a complete one and there may be other interacting drugs. Share the list of all present medication which you may be using with your doctor. Never start a new medication on your own.




It is unsafe to consume alcohol with Topamac 25mg Tablet.


Topamac 25mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

Topamac 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Topamac 25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.


Topamac 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Topamac 25mg Tablet may be needed. Please consult your doctor.


Topamac 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Topamac 25mg Tablet may be needed. Please consult your doctor.


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