Nelvir 250mg Nelfinavir Tablets

Nelvir

Nelvir Tablet is an antiviral agent which helps in the treatment of human immunodeficiency virus (HIV) infection.

nelvir

It doses not cure the disease but can reduce the chances of infections.
Monitoring of liver function and blood glucose levels is necessary while receiving this medicine. click here: Nelvir 

Side effects

Major & minor side effects for Nelvir Tablet

  • Diarrhea
  • Nausea and Vomiting
  • Abdominal pain
  • Increase in blood glucose level
  • Decrease in white blood cells and platelets
  • Itchy and dry skin
  • Headache
  • Weakness
  • Flatulence
  • Accumulation of body fat

Uses of Nelvir Tablet

What is it prescribed for?

  • HIV infection
    Nelvir Tablet is used in the treatment of HIV infection.

Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    This medicine is well absorbed from the Gastro-intestinal tract and reaches its peak levels in the body within 2 to 4 hours of administration.

  • How long do the effects of this medicine last?

    The effect of this medicine lasts for an average duration of 3.5 to 5 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit forming tendency has been reported.

  • Can this medicine be taken during pregnancy?

    This medicine is recommended in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

When not to use?

Allergy

Not recommended in patients with a known allergy to Nelvir Tablet.

Warnings

Warnings for special population

Pregnancy

This medicine is recommended in pregnant women only if necessary.
The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Bleeding disorder

Nelvir Tablet should be used with caution in patients with bleeding disorders like Hemophilia A or B. Inform the doctor if any unusual symptoms appear.
The dose of the medicine should be adjusted based on the clinical condition.

Diabetes

Nelvir Tablet may alter the blood glucose levels and also increases the risk of new-onset diabetes mellitus. Close monitoring of blood glucose levels is necessary while receiving this medicine.

Fat Redistribution

Nelvir Tablet may accumulate fat in the body and cause peripheral wasting, facial wasting, breast enlargement, and cushingoid appearance.
Close monitoring of body weight is necessary. Any changes in the body should be informed to the doctor.

Infections

Nelvir Tablet may suppress the immune response of the body and increase the risk of infections.

Any signs and symptoms of infection should be informed to the doctor.
Appropriate treatment should be initiated based on the clinical condition.

Dosage

Missed Dose

The missed dose should be taken as soon as one remembers.
However, if it is time for the next scheduled dose, then one should skip the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

General Instructions

Take Tablet as instructed by the doctor. Do not take in larger or smaller quantities than recommended.

Ensure that proper hygiene measures are adopted and complete the course of treatment to prevent the spread of the infection.
Close monitoring of liver function and blood glucose levels is necessary while receiving this medicine.

MEDICAL DESCRIPTION

tablet contains Nelfinavir 250mg. Nelvir (Nelfinavir (250mg)) tablet is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV) – 1 infection. Nelvir tablet is a protease inhibitor.
tablet works by reducing the viral load of HIV in your body. Nelvir tablet improves your immune system and reduces the risk of conditions associated with HIV infection. Nelvir tablet is used in combination with other antivirals for efficiency.

NELVIR 250MG TABLET USES

(Nelfinavir (250mg)) tablet is used to treat adults only who are infected by HIV-1. tablet must be taken in combination with other anti-HIV medicines. Your doctor will discuss which combination of medicines is best for you.

NELVIR 250MG TABLET BENEFITS

(Nelfinavir (250mg)) tablet is used with other anti-HIV medication to help control HIV infection. tablet helps to decrease the amount of HIV virus in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Nelvir tablet is protease inhibitor. Nelvir tablet is not a cure for HIV infection, it improves immunity that results in longevity of life. Nelvir tablet is recommended for use in children from age 2 and in adults.

NELVIR 250MG TABLET INDICATION

Nelvir (Nelfinavir (250mg)) tablet is indicated in the treatment of HIV-1 infection that causes AIDS in humans. tablet is used with other antiviral medications to boost the immunity of the affected hosts.  tablet is indicated in adults and children above age 2.

MECHANISM OF ACTION OF NELVIR 250MG TABLET

tablet contains Nelfinavir 250mg. Nelfinavir is a Protease inhibitor. Protease inhibitors are used as a part of highly active antiviral therapy (HAART) in HIV-infected patients.

Nelfinavir prevents HIV replication by binding to this specific enzyme thus selectively inhibits the cleavage of HIV-1 encoded Gag-Pol polyproteins in cells affected by the virus, thereby preventing the formation of mature virus particles into infectious virions that spreads the infection.

HOW NELVIR 250MG TABLET WORKS

(Nelfinavir (250mg)) tablet is a Protease inhibitor. Protease inhibitors are used as a part of highly active antiviral therapy (HAART) in HIV-infected patients. Nelfinavir prevents HIV replication by binding to this specific enzyme thus selectively inhibits the cleavage of HIV-1 encoded Gag-Pol polyproteins in cells affected by the virus, thereby preventing the formation of mature virus particles into infectious virions that spreads the infection.

NELVIR 250MG TABLET CONTRAINDICATION

Absolute contraindication:

  • if you are allergic to (Nelfinavir (250mg)) tablet
  • if you are pregnant
  • if you are diabetic

Relative contraindication:

  • if you have a liver disorder like hepatitis B or C or Child-Pugh disease
  • if you have blood disorders like hemolytic anemia
  • if you have renal diseases like phenylketonuria

NELVIR 250MG TABLET SIDE EFFECTS

Very common side effects that occur in more than 1:10 patients: Diarrhea

Common side effects that occur 1:10 patients: Nausea, Flatulence, Abdominal pain, Anemia, Allergic reaction, Impaired concentration, Lipodystrophy, Metabolic acidosis, Rash, Leukopenia, Thrombocytopenia, Weakness

Uncommon side effects that occur 1:100 patients: QTc prolongation, Torsades de pointes, Diabetes mellitus, new onset and exacerbation, Hyperglycemia

HOW TO TAKE NELVIR 250MG TABLET

Nelvir (Nelfinavir (250mg)) tablet is taken orally with food at a regular time

tablet can be taken by a child as an oral powder or crush the tablet but do not divide the crushed dosage.

After therapy has been initiated, do not take more or less of Nelvir medicine than prescribed or stop taking it without your physicians’ approval. Skipping or changing the tablet dose without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.

USE

If you are pregnant or breastfeeding inform your physician as they are not advisable.

The recommended dosage for tablet is 1250mg taken twice per day or 750mg taken twice per day

(Nelfinavir (250mg)) tablet must be taken with other antivirals as prescribed by the physician without fail. These medicines must be taken with food on a regular time basis.

USE OF NELVIR 250MG TABLET IN CHILDREN

The use of  (Nelfinavir (250mg)) tablet in less than 2 years of age is not recommended.

The recommended age is 2 to 13 years and dosage is calculated as 25-35 mg/kg given three times a day or 45-55mg/kg given two times a day

USE OF NELVIR 250MG TABLET IN ELDERLY PATIENTS

(Nelfinavir (250mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.

OTHER GENERAL WARNINGS

  • New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels. When needed add oral hypoglycemic and insulin
  • Blood disorders Hemophilia, hemolytic anemia
  • Skin reactions – It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
  • Musculoskeletal problems – Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
  • Accumulation or Redistribution of body fat or
  • immune reconstitution syndrome.
  • Any sign of infection – fever or lymph node enlargement
  • Lactose intolerance or galactose malabsorption

TALK TO YOUR DOCTOR IF

If you have any allergy

If you have a blood disorder

If you are pregnant or breastfeeding

GENERAL INSTRUCTIONS

(Nelfinavir (250mg)) tablet is taken with other antivirals orally as prescribed dosage at a specific time regularly.

DRUG INTERACTION OF TABLET

DRUG-DRUG INTERACTION

Acetylcholine – severity of adverse effects is increased thus consult your physician

Acyclovir – severity of adverse effects is increased thus consult your physician

Dopamine – severity of adverse effects is increased thus consult your physician

Esmolol – QTc prolongation is increased thus consult your physician

Norfloxacin – QTc prolongation is increased thus consult your physician

DRUG-FOOD INTERACTION

(Nelfinavir (250mg)) tablet can be safely taken with food, if doubts arise kindly refer to your physician. tablet generally causes side effects thus it is advised not to be taken with alcohol.

DRUG-DISEASE INTERACTION

  • Liver disorders – used with caution in severe liver diseases. Consult a physician before use
  • Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
  • Cardiac disorders – used with caution in prolonged QT syndrome. Consult a physician before use
  • Respiratory disorders – used with caution in respiratory distress and asthma. Consult a physician before use
  • Blood disorders – used with caution in hemolytic anemia and hemophilia. Consult a physician before use

OVER DOSE

Contact your doctor, pharmacist or nurse immediately.

MISSED DOSE

In general, if you take once a day dosage, the missed single dose of (Nelfinavir (250mg)) tablet can be taken within the next 12 hrs, you can take it. If it is more than 12 hrs, skip the dose and take the next dose at the recommended time. Don’t take a double dose for a forgotten dose.

PRECAUTIONS AND GENERAL WARNING OF NELVIR 250MG TABLET

ALCOHOL

(Nelfinavir (250mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

DRIVING OR OPERATING MACHINERY

It is preferred to drive or operate heavy machinery with caution as (Nelfinavir (250mg)) tablet causes side effects. For further queries, consult your physician.

PREGNANCY

The use of (Nelfinavir (250mg)) tablet is not recommended during pregnancy.

BREAST FEEDING

The use of (Nelfinavir (250mg)) tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effects in newborn.

KIDNEY PROBLEM

Renal filtration impairment and kidney stone formation – monitor function. For further queries, consult your physician.

LIVER DISEASE

Liver disorders and diseases like hepatitis B or C, Child-Pugh disease

Monitor liver function before and during therapy, especially in patients with other

FAQS FOR NELVIR 250MG TABLET

Is (Nelfinavir (250mg)) tablet safe during pregnancy?

No, tablet is not safe during pregnancy. Consult your physician.

Can tablet be taken while breastfeeding?

No, in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding.

Can tablet be taken while alcohol consumption?

The interaction is unknown but this medication causes side effects. Thus, consult your physician.

Can I take a drive or operate heavy machineries while on tablet?

This medication causes side effects thus caution is used while driving or operating machineries.

Can Nelvir tablet be taken separately as a treatment for HIV?

Nelvir tablet must be given with other antivirals.

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