Daclitof 60

Daclitof 60 Tablet is an antiviral medication used for the treatment of chronic hepatitis C in adults. It is normally used in a combination with sofosbuvir, with or without ribavirin. However, this medicine is not recommended for use as a preventive option for the spread of hepatitis C. click here: Daclitof

Daclitof 60

Side effects

Major & minor side effects for Daclitof 60 Tablet

  • Headache
  • Unusual tiredness
  • Nausea and Vomiting
  • Diarrhea
  • Anemia
  • Severe skin rash and hives
  • Dizziness
  • Sleep disturbances
  • Shortness of breath
  • Chest pain or discomfort
  • Mental confusion
  • Memory problems

Uses of Daclitof 60 Tablet

What is it prescribed for?

  • Chronic Hepatitis C
    This medicine is indicated for use with sofosbuvir, with or without ribavirin, for the treatment of Chronic Hepatitis C, an ongoing viral infection that damages the liver. Daclitof 60 can be used for both Hepatitis C Virus genotype 1 and genotype 3 infections.

Concerns

Commonly asked questions

How long does it take for this medicine to take effect?
The peak effect of this medicine can be observed within 2 hours of administration of the dose.

 

How long do the effects of this medicine last?
The amount of time for which this medicine remains active in the body is not clinically established.
Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. Daclitof 60 is advisable to consult your doctor before consumption.

 

Is this a habit forming medicine?
No habit-forming tendencies were reported.

 

Can this medicine be taken during pregnancy?
This Daclitof 60 is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

 

Can this medicine be taken while breastfeeding?
This Daclitof 60 is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

Allergy

This Daclitof 60 is not recommended for use in patients with a known allergy to daclatasvir, any other medicine used along with it as a part of combination therapy, or any other inactive ingredient present along with it. Contraindications of the individual medicines which are used along with daclatasvir as combinational therapy should also be considered before beginning treatment.

Strong CYP3A inducers

This Daclitof 60 is not recommended for use in patients receiving strong CYP3A inducers such as phenytoin, carbamazepine, rifampin, St.John’s wort, etc. due to the increased risk of worsening of the patient’s condition.

Warnings

Warnings for special population

Pregnancy

This Daclitof 60 is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This Daclitof 60 is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

Daclitof 60 Tablet may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Hepatitis B reactivation

Use of this Daclitof 60 in patients who also have hepatitis B may cause viral reactivation and potentially life-threatening side effects. Hence, it is advised to screen patients for hepatitis B infection before beginning therapy with this medicine.

Change in heart rate

Use of this medicine in a combination with sofosbuvir and amiodarone may increase the risk of decreased heart rate. This risk is especially higher in patients suffering from cardiac disorders and patients who are receiving beta blockers. An alternative treatment option may be necessary in some cases based on the clinical condition.

Tests prior to initiation of therapy

You may require to undergo certain tests like NS5A resistance testing in HCV genotype 1a- infected patients with cirrhosis before initiation of therapy.

Kidney impairment

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Limitation of use

Sustained virologic response (SVR12) rates are reduced in HCV genotype 3- infected patients with cirrhosis receiving this medicine in a combination with sofosbuvir for 12 weeks. An alternative treatment option may be necessary in such cases based on the clinical condition of the patient.

Driving or Operating machinery

Use of this Daclitof 60  may cause symptoms such as dizziness, confusion, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Dosage

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Dexamethasone
  • Atazanavir
  • Bosentan
  • Modafinil
  • Dabigatran
  • Efavirenz
  • Nevirapine
  • Digoxin
  • Clarithromycin
  • Ketoconazole
  • Atorvastatin

Disease interactions

  • Hepatitis B

In patients coinfected with hepatitis B and hepatitis C virus, the use of this medicine may cause a reactivation of HBV, causing life-threatening events. Hence, testing the patients for hepatitis B before initiating the treatment course with this medicine is recommended. An alternative treatment option may be necessary in some cases based on the clinical condition.

  • Food interactions

Information not available.

  • Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor. It is advised to continue the uptake of this medicine, even when symptoms resolve or improve until the therapy is completed.

 

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