Azmarda 200

AZMARDA 200MG contains two active substances, sacubitril and valsartan which is a medicine known as angiotensin receptor neprilysin inhibitor

Azmarda 200mg Tablet is a combination medicine used to treat heart failure. It reduces the risk of hospitalization and death due to long-lasting (chronic) heart failure.

Azmarda 200mg Tablet can be taken with or without food but is best taken at the same time(s) each day. Swallow it as a whole with water. Your dose, and how often you take it, will be decided by your doctor and may change depending on how well you respond to the medicine.

Keep taking the tablets regularly, as they have been prescribed, and try not to miss doses to get the most benefit. Do not stop taking them, even if you are feeling well. These tablets are preventing future harm.

Some of the common side effects include cough, dizziness, and feeling lightheaded. To reduce the risk of dizziness, try getting up slowly from a sitting or lying position. If these or other side effects are severe or do not go away, tell your doctor. Serious side effects are rare.

Before taking this medicine, tell your doctor if you are taking any other medicines for blood pressure or heart conditions or if you have kidney or liver disease.

Also let your doctor know all other medications you are using as they may affect, or be affected by, this medicine. This medicine should not be taken during pregnancy and is not recommended while breastfeeding.

While using it your blood pressure will need to be checked often and your kidney function may also need to be tested.

WHAT AZMARDA 200MG IS USED FOR?

AZMARDA 200MG is used to treat a type of long-term heart failure in adults
This type of heart failure occurs when the heart is weak and cannot pump enough blood to the lungs and the rest of the body

Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other parts of your body.

Azmarda 200mg Tablet is a combination of two medicine namely valsartan and sacubitril. Both of these medicines work in different ways to lower blood pressure. This makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.

This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

WARNING & PRECAUTION:

TALK TO DOCTOR

Tell your doctor before taking AZMARDA 200MG, if you:

• Are allergic to sacubitril, valsartan or any of the other ingredients of this medicine
• Or a member of your family have ever had a reaction called angioedema (swelling of the face, lips, tongue and/or throat, difficulties in breathing)
• Have diabetes or impaired kidney function
• Have severe liver disease
• Are suffering from dehydration

SAFETY ADVICE

Alcohol

UNSAFE

It is unsafe to consume alcohol with Azmarda 200mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Azmarda 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Azmarda 200mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Azmarda 200mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Azmarda 200mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Azmarda 200mg Tablet may be needed. Please consult your doctor.
Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.

Liver

CAUTION

Azmarda 200mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Azmarda 200mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate liver disease.

INTERACTIONS:

Tell your doctor, if you are taking, have recently taken or might take any other medicines.

This is particularly important for the following medicines:

• ACE inhibitors
• Other medicines used to treat heart failure or lower blood pressure, such as angiotensin receptor blockers or aliskiren
• Some medicines known as statins that are used to lower high cholesterol levels
• Sildenafil, a medicine used to treat erectile dysfunction or lung hypertension
• Medicines that increase the amount of potassium in the blood. These include potassium supplements, salt
• substitutes containing potassium, potassium-sparing medicines and heparin
• Painkillers of the type called non-steroidal anti-inflammatory medicines (NSAIDs) or selective cyclooxygenase-2 (Cox-2) inhibitors
• Lithium, a medicine used to treat some types of psychiatric illness
• Furosemide, a medicine belonging to the type known as diuretics, which are used to increase the amount of urine you produce
• Nitroglycerine, a medicine used to treat angina
• Some types of antibiotics (rifamycin group), ciclosporin (used to prevent rejection of transplanted organs) or antivirals such as ritonavir (used to treat HIV/AIDS)
• Metformin, a medicine used to treat diabetes

DIRECTIONS & FOR USE:

Always take this medicine exactly as your doctor has told you
You will usually start by taking 24 mg/26 mg or 49 mg/51 mg twice a day (one tablet in the morning and one tablet in the evening). Your doctor will decide your exact starting dose based on which medicines you have been taking previously

Your doctor will then adjust the dose depending on how you respond to the treatment until the best dose for you is found

The usual recommended target dose is 97 mg/103 mg twice a day (one tablet in the morning and one tablet in the evening)
Swallow the tablet with a glass of water.

You can take AZMARDA 200MG with or without food.

If you take more AZMARDA 200MG

If you have accidentally taken too many AZMARDA 200MG or if someone else has taken your tablets, contact your doctor immediately.

If you forget to take AZMARDA 200MG

It is advisable to take your medicine at the same time each day. However, if you forget to take a dose, you should simply take the next one at the scheduled time. Do not take a double dose to make up for a forgotten tablet.

If you stop taking AZMARDA 200MG

Stopping your treatment with AZMARDA 200MG may cause your condition to get worse. Do not stop taking your medicine unless your doctor tells you to.

SIDE EFFECTS OF AZMARDA 200MG:

SERIOUS

• Swelling of the face, lips, tongue and/or throat difficulties in breathing or swallowing. These may be signs of angioedema

COMMON

• Cough
• Diarrhoea, nausea, tiredness
• Low level of red blood cells (shown in a blood test)
• Low level of potassium in the blood (shown in a blood test)
• Headache, fainting, weakness
• Low blood pressure (dizziness, light-headedness) when switching from sitting or lying to standing position
• Gastritis (stomach pain, nausea)
• Spinning sensation
• Low level of sugar in the blood (shown in a blood test)
• Low blood pressure
• High level of potassium in the blood (shown in a blood test)
• Decreased renal function (renal impairment)

UNCOMMON

• Allergic reaction with rash and itching
• Dizziness when switching from sitting to standing position

STORAGE:

Keep this medicine out of reach of children
Do not use this medicine after the expiry date
Store at room temperature (15-25°C)